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The oxycodone in PERCOCET could result in spasm of your sphincter of Oddi. Opioids may well bring about boosts in serum amylase. Regularly evaluate individuals with biliary tract disease, together with acute pancreatitis, for worsening symptoms.Concomitant utilization of PERCOCET with CYP3A4 inducers or discontinuation of an CYP3A4 inhibitor could